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It has become increasingly well known in wellness, recovery, sports-performance, and longevity communities because of its proposed relationship to connective tissue, digestive wellness, circulation, inflammatory balance, and the body's natural repair processes
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In vitro experiments further disclosed the inhibitory effect of sUA on the monocyte Toll-like receptor (TLR) signaling pathway, which in turn reduces the migration capability of classical monocytes ( Macrophages Macrophages in most tissues have diverse functions, including initiating immune and inflammatory responses toward pathogens, maintaining tissue homeostasis, and contributing to tissue repair and remodeling ( Figure 2 )
